Spike sorting: the overlapping spikes challenge
نویسندگان
چکیده
منابع مشابه
Spike sorting of synchronous spikes from local neuron ensembles.
Synchronous spike discharge of cortical neurons is thought to be a fingerprint of neuronal cooperativity. Because neighboring neurons are more densely connected to one another than neurons that are located further apart, near-synchronous spike discharge can be expected to be prevalent and it might provide an important basis for cortical computations. Using microelectrodes to record local groups...
متن کاملSorting Overlapping Spike Waveforms from Electrode and Tetrode Recordings
One of the outstanding problems in the sorting of neuronal spike trains is the resolution of overlapping spikes. Resolving these spikes can significantly improve a range of analyses, such as response variability, correlation, and latency. In this paper, we describe a partially automated method that is capable of resolving overlapping spikes. After constructing template waveforms for well-isolat...
متن کاملA Brief Look into Spike Sorting Methods
Spike sorting is a class of techniques used in the analysis of electrophysiological data. Studying the dynamics of neural activity via electrical recording relies on the ability to detect and sort neural spikes recorded from a number of neurons by the same electrode. This article reviews methods for detecting and classifying action potentials, a problem commonly referred to as spike sorting.
متن کاملAutomatic sorting for multi-neuronal activity recorded with tetrodes in the presence of overlapping spikes.
Multi-neuronal recording is a powerful electrophysiological technique that has revealed much of what is known about the neuronal interactions in the brain. However, it is difficult to detect precise spike timings, especially synchronized simultaneous firings, among closely neighboring neurons recorded by one common electrode because spike waveforms overlap on the electrode when two or more neur...
متن کاملSpike sorting
Figure 1. Extracellular recordings and spike sorting. (A) The extracellular activity of neurons is recorded with microwires inserted in the brain. The spikes of neurons close-by the electrode tip (in red and blue) can be separated via spike sorting; neurons further away (in dark grey) can be detected but not sorted, thus generating the multiunit activity; more distant neurons (in light gray) co...
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ژورنال
عنوان ژورنال: Current Directions in Biomedical Engineering
سال: 2015
ISSN: 2364-5504
DOI: 10.1515/cdbme-2015-0011